1.
Indian J Biochem Biophys
;
1989 Oct; 26(5): 293-5
Article
in English
| IMSEAR
| ID: sea-26640
ABSTRACT
A soluble extract capable of transcribing Sarcoma-180 chromatin and DNA in a cell-free transcription system was prepared from Sarcoma-180 mouse ascites tumour cells. Incorporation of [3H]UTP into trichloroacetic acid-precipitable fraction is (i) reduced by 50% on removing DNase I hypersensitive sites of chromatin and (ii) inhibited by DNA binding antitumour anthracyclines, suggesting that this cell-free assay represents true transcription of active genes of Sarcoma-180 chromatin. Preparation of this soluble extract from mouse ascites tumour cells thus presents a very convenient way of studying cell-free transcription of active genes of chromatin and effect of antitumour agents on chromatin transcription.
Subject(s)
Animals , Antibiotics, Antineoplastic/pharmacology , Cell-Free System , Chromatin/metabolism , Mice , Sarcoma 180/genetics , Transcription, Genetic/drug effects , Tumor Cells, Cultured
2.
J Indian Med Assoc
;
1988 Mar; 86(3): 83-5
Article
in English
| IMSEAR
| ID: sea-104252
Subject(s)
Chronic Disease , Diarrhea, Infantile/epidemiology , Humans , India , Infant , Rural Health
3.
J Indian Med Assoc
;
1984 May; 82(5): 159-61
Article
in English
| IMSEAR
| ID: sea-96051
Subject(s)
Adult , Aged , Female , Follow-Up Studies , Humans , Hysterectomy, Vaginal , Middle Aged , Uterine Prolapse/surgery
4.
Indian Pediatr
;
1979 Oct; 16(10): 873-7
Article
in English
| IMSEAR
| ID: sea-7633
Subject(s)
Child , Child, Preschool , Cholinesterases/blood , Humans , Infant , Liver/pathology , Liver Function Tests , Thalassemia/enzymology
5.
J Indian Med Assoc
;
1976 Jul; 67(2): 37-40
Article
in English
| IMSEAR
| ID: sea-102026
6.
Indian J Cancer
;
1974 Sep; 11(3): 301-4
Article
in English
| IMSEAR
| ID: sea-50277
7.
J Indian Med Assoc
;
1967 May; 48(9): 438-40
Article
in English
| IMSEAR
| ID: sea-96440